Searchable abstracts of presentations at key conferences in endocrinology

ea0059p209 | Thyroid | SFEBES2018

Low dose rituximab for thyroid eye disease: an effective treatment with fall in TSH receptor antibodies (TRAb)

Suarez Annabel , Keren Shay , Norris Jonathan , David Joel , Turner Helen E

Background: Thyroid eye disease (TED) is an autoimmune inflammatory disease associated with GravesÂ’ disease. Rituximab (a monoclonal antibody that depletes B-cells), has recently been shown to be effective in treating TED. There is evidence to support an association with increased TRAbs and TED severity, and one study has demonstrated a fall in TRAbs with rituximab therapy. The aim of this study was to assess the clinical efficacy of low dose rituximab in patients with TE...